Trong nhi\u1ec1u th\u1eadp ni\u00ean, b\u1ec7nh nh\u00e2n t\u00ecm ki\u1ebfm thu\u1ed1c gi\u1ea3m \u0111au c\u00f3 hai l\u1ef1a ch\u1ecdn: thu\u1ed1c kh\u00f4ng k\u00ea \u0111\u01a1n nh\u01b0 aspirin ho\u1eb7c thu\u1ed1c opioid theo toa m\u1ea1nh nh\u01b0 oxycodone.<\/p>\n
C\u00e1c \u0111\u01a1n thu\u1ed1c opioid gi\u1ea3m m\u1ea1nh trong th\u1eadp ni\u00ean qua khi c\u00e1c b\u00e1c s\u0129 ng\u00e0y c\u00e0ng nh\u1eadn th\u1ee9c r\u00f5 h\u01a1n v\u1ec1 nguy c\u01a1 nghi\u1ec7n ng\u1eadp v\u00e0 l\u1ea1m d\u1ee5ng thu\u1ed1c trong th\u1eddi k\u1ef3 d\u1ecbch b\u1ec7nh ma t\u00fay \u0111ang di\u1ec5n ra tr\u00ean to\u00e0n qu\u1ed1c.<\/p>\n
G\u1ea7n \u0111\u00e2y, h\u00e3ng d\u01b0\u1ee3c ph\u1ea9m Vertex Pharmaceuticals \u00a0b\u00e1o c\u00e1o k\u1ebft qu\u1ea3 t\u00edch c\u1ef1c \u0111\u1ed1i v\u1edbi thu\u1ed1c gi\u1ea3m \u0111au kh\u00f4ng ch\u1ee9a opioid, m\u1ed9t trong s\u1ed1 c\u00e1c lo\u1ea1i thu\u1ed1c m\u00e0 nh\u00e0 s\u1ea3n xu\u1ea5t thu\u1ed1c c\u00f3 tr\u1ee5 s\u1edf t\u1ea1i Boston \u0111ang ph\u00e1t tri\u1ec3n \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb nhi\u1ec1u d\u1ea1ng \u0111au kh\u00e1c nhau.<\/p>\n
B\u1ec7nh nh\u00e2n d\u00f9ng thu\u1ed1c sau ph\u1eabu thu\u1eadt gi\u1ea3m \u0111au nhi\u1ec1u h\u01a1n so v\u1edbi nh\u1eefng ng\u01b0\u1eddi d\u00f9ng gi\u1ea3 d\u01b0\u1ee3c, m\u1eb7c d\u00f9 thu\u1ed1c kh\u00f4ng \u0111\u00e1p \u1ee9ng \u0111\u01b0\u1ee3c m\u1ee5c ti\u00eau th\u1ee9 y\u1ebfu l\u00e0 mang l\u1ea1i hi\u1ec7u qu\u1ea3 t\u1ed1t h\u01a1n \u0111i\u1ec1u tr\u1ecb b\u1eb1ng opioid.<\/p>\n
V\u1ec1 k\u1ebf ho\u1ea1ch nghi\u00ean c\u1ee9u lo\u1ea1i thu\u1ed1c m\u1edbi \u0111i\u1ec1u tr\u1ecb c\u01a1n \u0111au, Ti\u1ebfn S\u0129 David Altshuler, tr\u01b0\u1edfng nh\u00f3m c\u00e1c nh\u00e0 khoa h\u1ecdc c\u1ee7a Vertex n\u00f3i v\u1edbi AP: \u201cC\u00f3 nhu c\u1ea7u r\u1ea5t l\u1edbn v\u1ec1 c\u00e1c lo\u1ea1i thu\u1ed1c b\u1ed5 sung \u0111\u1ec3 gi\u00fap m\u1ecdi ng\u01b0\u1eddi ki\u1ec3m so\u00e1t c\u01a1n \u0111au. Tylenol c\u00f3 hi\u1ec7u qu\u1ea3 v\u1eeba ph\u1ea3i nh\u01b0ng l\u1ea1i \u0111\u01b0\u1ee3c dung n\u1ea1p r\u1ea5t t\u1ed1t, Opioid r\u1ea5t hi\u1ec7u qu\u1ea3 nh\u01b0ng g\u00e2y t\u00e1c d\u1ee5ng ph\u1ee5 c\u0169ng nh\u01b0 kh\u1ea3 n\u0103ng g\u00e2y nghi\u1ec7n.<\/p>\n
Vi\u1ec7c x\u00e1c \u0111\u1ecbnh c\u00e1c lo\u1ea1i thu\u1ed1c b\u1ed5 sung c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng cho nh\u1eefng ng\u01b0\u1eddi c\u1ea7n gi\u1ea3m \u0111au nhi\u1ec1u h\u01a1n nh\u01b0ng kh\u00f4ng mu\u1ed1n g\u1eb7p r\u1ee7i ro do opioid, s\u1ebd h\u1eefu \u00edch cho x\u00e3 h\u1ed9i.\u201d<\/p>\n
(minh h\u1ecda: Roberto Sorin\/Unsplash)<\/p>\n
Ti\u1ebfn S\u0129 Altshuler cho bi\u1ebft th\u00eam, h\u1ecd \u0111\u00e3 nghi\u00ean c\u1ee9u v\u1ea5n \u0111\u1ec1 n\u00e0y trong 20 n\u0103m v\u00e0 hi\u1ec3u bi\u1ebft s\u00e2u s\u1eafc d\u1eabn \u0111\u1ebfn vi\u1ec7c t\u1ea1o ra c\u00e1c lo\u1ea1i thu\u1ed1c n\u00e0y th\u1ef1c s\u1ef1 \u0111\u1ebfn t\u1eeb c\u00e1c nghi\u00ean c\u1ee9u v\u1ec1 nh\u1eefng ng\u01b0\u1eddi m\u1eafc m\u1ed9t c\u0103n b\u1ec7nh hi\u1ebfm g\u1eb7p khi\u1ebfn b\u1ec7nh nh\u00e2n kh\u00f4ng nh\u1ea1y c\u1ea3m v\u1edbi c\u01a1n \u0111au. H\u1ecd c\u00f3 th\u1ec3 c\u1ea3m nh\u1eadn \u0111\u01b0\u1ee3c m\u1ecdi th\u1ee9, c\u1ea3m nh\u1eadn \u0111\u01b0\u1ee3c nhi\u1ec7t \u0111\u1ed9 nh\u01b0ng kh\u00f4ng c\u1ea3m th\u1ea5y \u0111au. \u0110i\u1ec1u n\u00e0y \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh khi m\u1ed9t ng\u01b0\u1eddi \u0111i c\u00f3 th\u1ec3 b\u01b0\u1edbc tr\u00ean than n\u00f3ng.<\/p>\n
C\u00e1c nh\u00e0 khoa h\u1ecdc ph\u00e1t hi\u1ec7n ra r\u1eb1ng \u0111\u00f3 l\u00e0 do s\u1ef1 kh\u00e1c bi\u1ec7t di truy\u1ec1n \u1edf m\u1ed9t lo\u1ea1i protein c\u1ee5 th\u1ec3 c\u00f3 vai tr\u00f2 truy\u1ec1n t\u00edn hi\u1ec7u \u0111au, v\u00ec v\u1eady n\u1ebfu thi\u1ebfu ch\u1ee9c n\u0103ng n\u00e0y, b\u1ea1n s\u1ebd kh\u00f4ng c\u1ea3m th\u1ea5y \u0111au.<\/p>\n
\u201cCh\u00fang t\u00f4i v\u00e0 nhi\u1ec1u ng\u01b0\u1eddi kh\u00e1c \u0111\u00e3 l\u00e0m vi\u1ec7c trong nhi\u1ec1u th\u1eadp k\u1ef7 \u0111\u1ec3 t\u1ea1o ra m\u1ed9t lo\u1ea1i thu\u1ed1c c\u00f3 th\u1ec3 kh\u1eafc ph\u1ee5c hi\u1ec7n t\u01b0\u1ee3ng t\u1ef1 nhi\u00ean \u0111\u00f3,\u201d Ti\u1ebfn S\u0129 Altshuler n\u00f3i.<\/p>\n
Theo \u00f4ng, thu\u1ed1c g\u00e2y nghi\u1ec7n th\u01b0\u1eddng ho\u1ea1t \u0111\u1ed9ng trong n\u00e3o v\u00e0 c\u00f3 t\u00e1c d\u1ee5ng ph\u1ee5 kh\u00f4ng th\u1ef1c s\u1ef1 t\u00e1ch bi\u1ec7t \u0111\u01b0\u1ee3c v\u1edbi vi\u1ec7c gi\u1ea3m \u0111au, v\u00ec ch\u00fang gi\u1ed1ng nhau. C\u00f2n c\u00e1c lo\u1ea1i thu\u1ed1c gi\u1ea3m \u0111au kh\u00f4ng g\u00e2y nghi\u1ec7n, l\u00e0 v\u00ec thu\u1ed1c ho\u1ea1t \u0111\u1ed9ng \u1edf ngo\u1ea1i vi ch\u1ee9 kh\u00f4ng ph\u1ea3i \u1edf n\u00e3o, n\u00ean kh\u00f4ng c\u00f3 c\u00f9ng nguy c\u01a1 ti\u1ec1m \u1ea9n.<\/p>\n
Vi\u1ec7c th\u1eed nghi\u1ec7m \u0111\u00e3 \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n \u1edf ba tr\u01b0\u1eddng h\u1ee3p b\u1ecb \u0111au c\u1ea5p t\u00ednh do gi\u1ea3i ph\u1eabu ho\u1eb7c b\u1ecb ch\u1ea5n th\u01b0\u01a1ng. C\u1ea3 ba tr\u01b0\u1eddng h\u1ee3p \u0111\u1ec1u cho ra k\u1ebft qu\u1ea3 t\u00edch c\u1ef1c, cho th\u1ea5y m\u1ee9c \u0111\u1ed9 gi\u1ea3m \u0111au \u0111\u00e1ng k\u1ec3 kho\u1ea3ng 50%.<\/p>\n
C\u00e1c nh\u00e0 khoa h\u1ecdc c\u0169ng th\u1ef1c hi\u1ec7n m\u1ed9t nghi\u00ean c\u1ee9u v\u1ec1 b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean do ti\u1ec3u \u0111\u01b0\u1eddng, m\u1ed9t c\u01a1n \u0111au k\u00e9o d\u00e0i g\u00e2y ra khi nh\u1eefng ng\u01b0\u1eddi m\u1eafc b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng b\u1ecb t\u1ed5n th\u01b0\u01a1ng d\u00e2y th\u1ea7n kinh.<\/p>\n
\u0110\u00f3 c\u0169ng l\u00e0 m\u1ed9t nghi\u00ean c\u1ee9u t\u00edch c\u1ef1c cho th\u1ea5y s\u1ef1 gi\u1ea3m \u0111au c\u00f3 \u00fd ngh\u0129a l\u00e2m s\u00e0ng. D\u1ef1a tr\u00ean nghi\u00ean c\u1ee9u \u0111\u00f3, c\u00e1c nh\u00e0 khoa h\u1ecdc s\u1ebd ti\u1ebfn h\u00e0nh giai \u0111o\u1ea1n 2, v\u00e0 \u0111ang l\u00ean k\u1ebf ho\u1ea1ch cho nghi\u00ean c\u1ee9u giai \u0111o\u1ea1n 3.<\/p>\n
Vertex \u0111ang chu\u1ea9n b\u1ecb n\u1ed9p \u0111\u01a1n l\u00ean FDA \u0111\u1ec3 \u0111\u01b0\u1ee3c ch\u1ea5p thu\u1eadn lo\u1ea1i thu\u1ed1c tr\u1ecb nh\u1eefng c\u01a1n \u0111au c\u1ea5p t\u00ednh. \u0110\u1ed1i v\u1edbi c\u01a1n \u0111au d\u00e0i h\u1ea1n (\u0111au th\u1ea7n kinh) c\u0169ng cho ra d\u1eef li\u1ec7u \u0111\u00e1ng kh\u00edch l\u1ec7, \u0111ang \u0111\u01b0\u1ee3c ti\u1ebfp t\u1ee5c nghi\u00ean c\u1ee9u.<\/p>\n
The post T\u00edn hi\u1ec7u t\u1ed1t t\u1eeb lo\u1ea1i thu\u1ed1c gi\u1ea3m \u0111au kh\u00f4ng g\u00e2y nghi\u1ec7n<\/a> appeared first on Saigon Nh\u1ecf<\/a>.<\/p>\n \u00a0<\/p>","protected":false},"excerpt":{"rendered":" Trong nhi\u1ec1u th\u1eadp ni\u00ean, b\u1ec7nh nh\u00e2n t\u00ecm ki\u1ebfm thu\u1ed1c gi\u1ea3m \u0111au c\u00f3 hai l\u1ef1a ch\u1ecdn: thu\u1ed1c kh\u00f4ng k\u00ea \u0111\u01a1n nh\u01b0 aspirin ho\u1eb7c thu\u1ed1c opioid theo toa m\u1ea1nh nh\u01b0 oxycodone. C\u00e1c \u0111\u01a1n thu\u1ed1c opioid gi\u1ea3m m\u1ea1nh trong th\u1eadp ni\u00ean qua khi c\u00e1c b\u00e1c s\u0129 ng\u00e0y c\u00e0ng nh\u1eadn th\u1ee9c r\u00f5 h\u01a1n v\u1ec1 nguy c\u01a1 nghi\u1ec7n ng\u1eadp v\u00e0 …<\/p>","protected":false},"author":0,"featured_media":50133,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[82,43],"tags":[],"class_list":["post-50132","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-society","category-health"],"_links":{"self":[{"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/posts\/50132","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/comments?post=50132"}],"version-history":[{"count":0,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/posts\/50132\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/media\/50133"}],"wp:attachment":[{"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/media?parent=50132"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/categories?post=50132"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/tags?post=50132"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}