C\u00e1c nh\u00e0 khoa h\u1ecdc v\u1eeba t\u00ecm ra c\u00e1ch virus herpes g\u00e2y b\u1ec7nh nguy hi\u1ec3m x\u00e2m nh\u1eadp v\u00e0o t\u1ebf b\u00e0o c\u1ee7a con ng\u01b0\u1eddi nh\u01b0 th\u1ebf n\u00e0o. Theo Newsweek.<\/p>\n
Theo m\u1ed9t b\u00e0i b\u00e1o m\u1edbi tr\u00ean t\u1ea1p ch\u00ed Proceedings c\u1ee7a Vi\u1ec7n H\u00e0n L\u00e2m Khoa H\u1ecdc Qu\u1ed1c Gia (National Academy of Sciences), virus Herpes simplex lo\u1ea1i 1, nguy\u00ean nh\u00e2n ch\u00ednh g\u00e2y ra b\u1ec7nh m\u1ee5n r\u1ed9p \u1edf mi\u1ec7ng, x\u00e2m nh\u1eadp v\u00e0o c\u00e1c t\u1ebf b\u00e0o th\u1ea7n kinh b\u1eb1ng c\u00e1ch th\u1ef1c hi\u1ec7n c\u00e1c qu\u00e1 tr\u00ecnh di chuy\u1ec3n t\u1ebf b\u00e0o.<\/p>\n
Kh\u00e1m ph\u00e1 n\u00e0y gi\u00fap c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u ph\u00e1t tri\u1ec3n c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb m\u1edbi v\u00e0 hi\u1ec7u qu\u1ea3 h\u01a1n \u0111\u1ed1i v\u1edbi lo\u1ea1i virus ph\u1ed5 bi\u1ebfn n\u00e0y.<\/p>\n
Herpes simplex lo\u1ea1i 1 (HSV-1) ch\u1ee7 y\u1ebfu g\u00e2y ra b\u1ec7nh m\u1ee5n r\u1ed9p \u1edf mi\u1ec7ng c\u00f3 th\u1ec3 g\u00e2y b\u00f9ng ph\u00e1t c\u00e1c v\u1ebft lo\u00e9t l\u1ea1nh tr\u00ean v\u00e0 xung quanh mi\u1ec7ng, khi\u1ebfn ng\u01b0\u1eddi b\u1ec7nh r\u1ea5t \u0111au. Kho\u1ea3ng 67% (3.7 t\u1ef7 ng\u01b0\u1eddi) s\u1ed1 ng\u01b0\u1eddi d\u01b0\u1edbi 50 tu\u1ed5i tr\u00ean to\u00e0n th\u1ebf gi\u1edbi b\u1ecb nhi\u1ec5m lo\u1ea1i virus n\u00e0y.<\/p>\n
Herpes simplex lo\u1ea1i\u00a02 (HSV-2) ch\u1ee7 y\u1ebfu g\u00e2y ra b\u1ec7nh m\u1ee5n r\u1ed9p sinh d\u1ee5c, v\u1edbi 13% (kho\u1ea3ng 490 tri\u1ec7u ng\u01b0\u1eddi) s\u1ed1 ng\u01b0\u1eddi trong \u0111\u1ed9 tu\u1ed5i t\u1eeb 15 \u0111\u1ebfn 49 tr\u00ean th\u1ebf gi\u1edbi b\u1ecb nhi\u1ec5m lo\u1ea1i virus n\u00e0y.<\/p>\n
Nh\u1eefng b\u1ec7nh nhi\u1ec5m virus n\u00e0y l\u00e2y lan qua ti\u1ebfp x\u00fac da k\u1ec1 da, th\u01b0\u1eddng l\u00e0 h\u00f4n \u0111\u1ed1i v\u1edbi HSV-1 v\u00e0 quan h\u1ec7 t\u00ecnh d\u1ee5c \u0111\u1ed1i v\u1edbi HSV-2, l\u00e2y nhi\u1ec5m v\u00e0o c\u00e1c t\u1ebf b\u00e0o th\u1ea7n kinh. Nhi\u1ec1u ng\u01b0\u1eddi kh\u00f4ng c\u00f3 b\u1ea5t k\u1ef3 tri\u1ec7u ch\u1ee9ng n\u00e0o c\u1ee7a nhi\u1ec5m tr\u00f9ng herpes simplex, nh\u01b0ng nh\u1eefng ng\u01b0\u1eddi b\u1ecb m\u1ee5n n\u01b0\u1edbc \u0111au \u0111\u1edbn \u1edf v\u00f9ng b\u1ecb nhi\u1ec5m b\u1ec7nh c\u00f3 kh\u1ea3 n\u0103ng t\u00e1i ph\u00e1t sau m\u1ed9t th\u1eddi gian d\u00e0i kh\u00f4ng ho\u1ea1t \u0111\u1ed9ng.<\/p>\n
C\u00e1c t\u00e1c nh\u00e2n g\u00e2y b\u00f9ng ph\u00e1t t\u00e1i ph\u00e1t bao g\u1ed3m ti\u1ebfp x\u00fac v\u1edbi \u00e1nh n\u1eafng m\u1eb7t tr\u1eddi, c\u0103ng th\u1eb3ng, ph\u1eabu thu\u1eadt, b\u1ec7nh t\u1eadt ho\u1eb7c s\u1ed1t. Hi\u1ec7n ch\u01b0a c\u00f3 ph\u01b0\u01a1ng ph\u00e1p ch\u1eefa tr\u1ecb n\u00e0o \u0111\u1ed1i v\u1edbi t\u00ecnh tr\u1ea1ng nhi\u1ec5m tr\u00f9ng do nh\u1eefng lo\u1ea1i virus n\u00e0y g\u00e2y ra v\u00ec ch\u00fang tr\u00fa \u1ea9n trong h\u1ec7 th\u1ed1ng th\u1ea7n kinh.<\/p>\n
Theo b\u00e0i b\u00e1o m\u1edbi, m\u1ee5n r\u1ed9p c\u00f3 kh\u1ea3 n\u0103ng x\u00e2m nh\u1eadp v\u00e0o c\u00e1c t\u1ebf b\u00e0o th\u1ea7n kinh c\u1ee7a con ng\u01b0\u1eddi b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng c\u00e1c c\u1ea5u tr\u00fac g\u1ecdi l\u00e0 vi \u1ed1ng v\u00e0 s\u1eed d\u1ee5ng c\u00e1c \u0111\u1ed9ng c\u01a1 protein \u0111\u1eb7c bi\u1ec7t c\u00f3 t\u00ean l\u00e0 dynein v\u00e0 kinesin \u0111\u1ec3 di chuy\u1ec3n.<\/p>\n
Dynein l\u00e0 m\u1ed9t lo\u1ea1i protein nh\u1ecf trong t\u1ebf b\u00e0o, ho\u1ea1t \u0111\u1ed9ng gi\u1ed1ng nh\u01b0 m\u1ed9t \u0111\u1ed9ng c\u01a1 nh\u1ecf v\u00e0 gi\u00fap di chuy\u1ec3n m\u1ecdi th\u1ee9 b\u00ean trong t\u1ebf b\u00e0o, nh\u01b0 th\u1ee9c \u0103n, ch\u1ea5t th\u1ea3i v\u00e0 c\u00e1c ch\u1ea5t kh\u00e1c \u0111\u1ebfn n\u01a1i c\u1ea7n \u0111\u1ebfn. Dynein ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u0111i d\u1ecdc theo c\u00e1c r\u00e3nh b\u00ean trong t\u1ebf b\u00e0o g\u1ecdi l\u00e0 vi \u1ed1ng, ch\u1ee7 y\u1ebfu h\u01b0\u1edbng v\u1ec1 ph\u00eda trung t\u00e2m t\u1ebf b\u00e0o.<\/p>\n
Kinesin l\u00e0 m\u1ed9t lo\u1ea1i protein v\u1eadn \u0111\u1ed9ng kh\u00e1c, gi\u1ed1ng nh\u01b0 dynein, nh\u01b0ng n\u00f3 th\u01b0\u1eddng di chuy\u1ec3n theo h\u01b0\u1edbng ng\u01b0\u1ee3c l\u1ea1i. Kinesin \u201c\u0111i\u201d d\u1ecdc theo c\u00e1c vi \u1ed1ng gi\u1ed1ng nh\u01b0 dynein, nh\u01b0ng th\u01b0\u1eddng h\u01b0\u1edbng v\u1ec1 ph\u00eda c\u00e1c ph\u1ea7n b\u00ean ngo\u00e0i c\u1ee7a t\u1ebf b\u00e0o.<\/p>\n
T\u00e1c gi\u1ea3 nghi\u00ean c\u1ee9u Gregory Smith, gi\u00e1o s\u01b0 vi sinh v\u00e0 mi\u1ec5n d\u1ecbch h\u1ecdc t\u1ea1i Northwestern University, cho bi\u1ebft: \u201cC\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111ang ph\u00e1t tri\u1ec3n vaccine ch\u1ed1ng l\u1ea1i nh\u1eefng lo\u1ea1i virus n\u00e0y v\u00e0 nh\u1eefng lo\u1ea1i vaccine \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf \u0111\u1eb7c bi\u1ec7t \u0111\u1ec3 kh\u00f4ng x\u00e2m nh\u1eadp v\u00e0o h\u1ec7 th\u1ea7n kinh. Ch\u00fang t\u00f4i bi\u1ebft c\u00e1ch bi\u1ebfn \u0111\u1ed5i virus \u0111\u1ec3 ch\u00fang kh\u00f4ng x\u00e2m nh\u1eadp v\u00e0o h\u1ec7 th\u1ea7n kinh, nh\u01b0ng hi\u1ec7n t\u1ea1i v\u1eabn ch\u01b0a hi\u1ec3u \u0111\u1ea7y \u0111\u1ee7 v\u1ec1 m\u1eb7t c\u01a1 h\u1ecdc, t\u1ea1i sao s\u1ef1 \u0111\u1ed9t bi\u1ebfn l\u1ea1i hi\u1ec7u qu\u1ea3 \u0111\u1ebfn v\u1eady.\u201d<\/p>\n
(H\u00ecnh minh h\u1ecda: NCI\/Unsplash)<\/p>\n
C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u t\u1eeb Northwestern University m\u00f4 t\u1ea3 c\u00e1ch h\u1ecd g\u1eafn c\u00e1c d\u1ea5u hi\u1ec7u hu\u1ef3nh quang \u0111\u1eb7c bi\u1ec7t v\u00e0o virus \u0111\u1ec3 theo d\u00f5i c\u00e1ch n\u00f3 di chuy\u1ec3n trong t\u1ebf b\u00e0o b\u1ecb nhi\u1ec5m b\u1ec7nh. H\u1ecd ph\u00e1t hi\u1ec7n ra r\u1eb1ng m\u1ed9t lo\u1ea1i protein trong virus c\u00f3 t\u00ean pUL37 \u0111\u00e3 chi\u1ebfm quy\u1ec1n \u0111i\u1ec1u khi\u1ec3n v\u00e0 v\u00f4 hi\u1ec7u h\u00f3a kinesin c\u1ee7a t\u1ebf b\u00e0o \u0111\u1ec3 \u0111\u1ea9y nhanh h\u00e0nh tr\u00ecnh c\u1ee7a n\u00f3 v\u00e0o nh\u00e2n t\u1ebf b\u00e0o th\u1ea7n kinh.<\/p>\n
\u0110\u1ed3ng t\u00e1c gi\u1ea3 nghi\u00ean c\u1ee9u DongHo Kim, m\u1ed9t nghi\u00ean c\u1ee9u sinh ti\u1ebfn s\u0129 t\u1ea1i ph\u00f2ng th\u00ed nghi\u1ec7m Smith, cho bi\u1ebft: \u201cPh\u00e1t hi\u1ec7n c\u1ee7a ch\u00fang t\u00f4i ch\u1ee9ng minh c\u00e1ch c\u00e1c alphaherpesvirus, ch\u1eb3ng h\u1ea1n nh\u01b0 HSV-1, ti\u1ebfn h\u00f3a \u0111\u1ec3 tr\u1edf n\u00ean c\u00f3 hi\u1ec7u qu\u1ea3 cao trong vi\u1ec7c x\u00e2m chi\u1ebfm h\u1ec7 th\u1ea7n kinh. Virus\u00a0\u0111\u1ea1t \u0111\u01b0\u1ee3c \u0111i\u1ec1u n\u00e0y b\u1eb1ng c\u00e1ch \u0111i\u1ec1u ch\u1ec9nh protein v\u1eadn \u0111\u1ed9ng kinesin theo kh\u00f4ng gian v\u00e0 th\u1eddi gian \u0111\u1ec3 cho ph\u00e9p v\u1eadn chuy\u1ec3n c\u00e1c h\u1ea1t virus\u00a0\u0111\u1ebfn nh\u00e2n m\u1ed9t c\u00e1ch tr\u01a1n tru. Vi\u1ec7c kh\u00f4ng \u0111i\u1ec1u ch\u1ec9nh \u0111\u01b0\u1ee3c v\u1eadn \u0111\u1ed9ng kinesin s\u1ebd khi\u1ebfn n\u00f3 tham gia v\u00e0o m\u1ed9t cu\u1ed9c gi\u1eb1ng co v\u1edbi \u0111\u1ed9ng c\u01a1 dynein \u0111\u1ed1i l\u1eadp, v\u00e0 virus\u00a0kh\u00f4ng th\u1ec3 di chuy\u1ec3n theo h\u01b0\u1edbng n\u00e0y hay h\u01b0\u1edbng kh\u00e1c.\u201d<\/p>\n
C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u hy v\u1ecdng c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng nh\u1eefng kh\u00e1m ph\u00e1 n\u00e0y \u0111\u1ec3 t\u1ea1o ra c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb m\u1edbi cho b\u1ec7nh l\u00e2y nhi\u1ec5m herpes. \u00d4ng Kim cho bi\u1ebft: \u201cT\u00f4i ngh\u0129 m\u00f4 h\u00ecnh c\u1ee7a ch\u00fang t\u00f4i b\u1ed5 sung m\u1ed9t b\u01b0\u1edbc quan tr\u1ecdng trong vi\u1ec7c t\u00ecm hi\u1ec3u qu\u00e1 tr\u00ecnh x\u00e2m l\u1ea5n th\u1ea7n kinh c\u1ee7a HSV-1 v\u00e0 c\u00e1 nh\u00e2n t\u00f4i r\u1ea5t vui m\u1eebng khi th\u1ea5y c\u00e1ch c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng cho c\u00e1c li\u1ec7u ph\u00e1p ti\u1ec1m n\u0103ng.\u201d<\/p>\n
V\u1edbi s\u1ef1 hi\u1ec3u bi\u1ebft m\u1edbi n\u00e0y, gi\u1edd \u0111\u00e2y khoa h\u1ecdc c\u00f3 kh\u1ea3 n\u0103ng \u0111i s\u00e2u h\u01a1n v\u00e0o qu\u00e1 tr\u00ecnh \u0111\u01b0\u1ee3c d\u00e0n d\u1ef1ng nh\u1eb1m \u0111\u01b0a v\u1eadt li\u1ec7u di truy\u1ec1n virus t\u1eeb th\u1ebf gi\u1edbi b\u00ean ngo\u00e0i v\u00e0o t\u1ebf b\u00e0o th\u1ea7n kinh c\u1ee7a con ng\u01b0\u1eddi.<\/p>\n
The post Ph\u00e1t hi\u1ec7n m\u1edbi v\u1ec1 virus herpes g\u00e2y b\u1ec7nh nguy hi\u1ec3m<\/a> appeared first on Saigon Nh\u1ecf<\/a>.<\/p>\n \u00a0<\/p>","protected":false},"excerpt":{"rendered":" C\u00e1c nh\u00e0 khoa h\u1ecdc v\u1eeba t\u00ecm ra c\u00e1ch virus herpes g\u00e2y b\u1ec7nh nguy hi\u1ec3m x\u00e2m nh\u1eadp v\u00e0o t\u1ebf b\u00e0o c\u1ee7a con ng\u01b0\u1eddi nh\u01b0 th\u1ebf n\u00e0o. Theo Newsweek. Theo m\u1ed9t b\u00e0i b\u00e1o m\u1edbi tr\u00ean t\u1ea1p ch\u00ed Proceedings c\u1ee7a Vi\u1ec7n H\u00e0n L\u00e2m Khoa H\u1ecdc Qu\u1ed1c Gia (National Academy of Sciences), virus Herpes simplex lo\u1ea1i 1, nguy\u00ean nh\u00e2n …<\/p>","protected":false},"author":0,"featured_media":51163,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[82,43],"tags":[],"class_list":["post-51162","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-society","category-health"],"_links":{"self":[{"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/posts\/51162","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/comments?post=51162"}],"version-history":[{"count":0,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/posts\/51162\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/media\/51163"}],"wp:attachment":[{"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/media?parent=51162"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/categories?post=51162"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/tags?post=51162"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}