M\u1ed9t nghi\u00ean c\u1ee9u m\u1edbi cho th\u1ea5y Semaglutide, th\u00e0nh ph\u1ea7n ho\u1ea1t ch\u1ea5t trong thu\u1ed1c gi\u1ea3m c\u00e2n Ozempic v\u00e0 Wegovy, c\u00f3 li\u00ean quan \u0111\u1ebfn vi\u1ec7c t\u0103ng nguy c\u01a1 m\u1eafc c\u00e1c b\u1ec7nh v\u1ec1 m\u1eaft g\u00e2y gi\u1ea3m th\u1ecb l\u1ef1c.<\/p>\n
C\u00e1c nh\u00e0 khoa h\u1ecdc t\u1ea1i tr\u01b0\u1eddng Harvard School of Public Health ch\u1ec9 ra m\u1ed1i li\u00ean h\u1ec7 gi\u1eefa Ozempic v\u00e0 kh\u1ea3 n\u0103ng ph\u00e1t tri\u1ec3n b\u1ec7nh th\u1ea7n kinh th\u1ecb gi\u00e1c thi\u1ebfu m\u00e1u c\u1ee5c b\u1ed9 ph\u00eda tr\u01b0\u1edbc kh\u00f4ng do vi\u00eam \u0111\u1ed9ng m\u1ea1ch (Nonarteritic Anterior Ischemic Optic Neuropathy \u2013 NAION), \u0111\u01b0\u1ee3c bi\u1ebft l\u00e0 nguy\u00ean nh\u00e2n g\u00e2y m\u1ea5t th\u1ecb l\u1ef1c \u0111\u1ed9t ng\u1ed9t \u1edf m\u1ed9t m\u1eaft do gi\u1ea3m l\u01b0u l\u01b0\u1ee3ng m\u00e1u \u0111\u1ebfn d\u00e2y th\u1ea7n kinh th\u1ecb gi\u00e1c. Nh\u1eefng ng\u01b0\u1eddi m\u1eafc b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng ph\u1ea3i \u0111\u1ed1i m\u1eb7t v\u1edbi nguy c\u01a1 cao m\u1eafc c\u0103n b\u1ec7nh hi\u1ebfm th\u1ea5y n\u00e0y.<\/p>\n
Novo Nordisk, c\u00f4ng ty d\u01b0\u1ee3c ph\u1ea9m s\u1ea3n xu\u1ea5t thu\u1ed1c, cho bi\u1ebft d\u1eef li\u1ec7u c\u1ee7a nghi\u00ean c\u1ee9u kh\u00f4ng x\u00e1c nh\u1eadn b\u1ea5t k\u1ef3 m\u1ed1i li\u00ean h\u1ec7 nh\u00e2n qu\u1ea3 n\u00e0o gi\u1eefa semaglutide v\u00e0 t\u00ecnh tr\u1ea1ng n\u00e0y. C\u00e1c t\u00e1c gi\u1ea3 nghi\u00ean c\u1ee9u c\u0169ng th\u1eeba nh\u1eadn vi\u1ec7c h\u1ecd c\u1ea7n th\u1eed nghi\u1ec7m th\u00eam.<\/p>\n
Th\u1eed nghi\u1ec7m \u0111\u00e3 s\u1eed d\u1ee5ng d\u1eef li\u1ec7u b\u1ec7nh nh\u00e2n c\u1ee7a ph\u00f2ng kh\u00e1m m\u1eaft \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh 710 ng\u01b0\u1eddi \u0111ang \u0111i\u1ec1u tr\u1ecb b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng Type 2 v\u00e0 979 ng\u01b0\u1eddi \u0111i\u1ec1u tr\u1ecb b\u00e9o ph\u00ec b\u1eb1ng semaglutide ho\u1eb7c m\u1ed9t lo\u1ea1i thu\u1ed1c ho\u00e0n to\u00e0n kh\u00e1c.<\/p>\n
Ng\u01b0\u1eddi ta ph\u00e1t hi\u1ec7n ra r\u1eb1ng, trong kho\u1ea3ng th\u1eddi gian ba n\u0103m, 8.9% b\u1ec7nh nh\u00e2n ti\u1ec3u \u0111\u01b0\u1eddng s\u1eed d\u1ee5ng semaglutide \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n m\u1eafc NAION, so v\u1edbi 1.8% nh\u1eefng ng\u01b0\u1eddi d\u00f9ng thu\u1ed1c kh\u00e1c.<\/p>\n
Trong nh\u00f3m th\u1eeba c\u00e2n v\u00e0 b\u00e9o ph\u00ec, nguy c\u01a1 ph\u00e1t tri\u1ec3n b\u1ec7nh v\u1ec1 m\u1eaft l\u00e0 6.7% so v\u1edbi 0.8% \u1edf nh\u00f3m d\u00f9ng thu\u1ed1c kh\u00e1c.<\/p>\n
Ph\u00e1t ng\u00f4n vi\u00ean c\u1ee7a c\u00f4ng ty d\u01b0\u1ee3c ph\u1ea9m Novo Nordisk n\u00f3i v\u1edbi Newsweek: \u201cAn to\u00e0n cho b\u1ec7nh nh\u00e2n l\u00e0 \u01b0u ti\u00ean h\u00e0ng \u0111\u1ea7u c\u1ee7a Novo Nordisk v\u00e0 ch\u00fang t\u00f4i r\u1ea5t coi tr\u1ecdng t\u1ea5t c\u1ea3 c\u00e1c b\u00e1o c\u00e1o v\u1ec1 t\u00e1c d\u1ee5ng ph\u1ee5 do s\u1eed d\u1ee5ng thu\u1ed1c c\u1ee7a c\u00f4ng ty. Nh\u00ecn chung, d\u1eef li\u1ec7u \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 trong nghi\u00ean c\u1ee9u kh\u00f4ng \u0111\u1ee7 \u0111\u1ec3 thi\u1ebft l\u1eadp m\u1ed1i li\u00ean h\u1ec7 nh\u00e2n qu\u1ea3 gi\u1eefa vi\u1ec7c s\u1eed d\u1ee5ng GLP-1RA semaglutide v\u00e0 NAION. NAION kh\u00f4ng ph\u1ea3i l\u00e0 m\u1ed9t ph\u1ea3n \u1ee9ng c\u00f3 h\u1ea1i c\u1ee7a thu\u1ed1c \u0111\u1ed1i v\u1edbi c\u00e1c c\u00f4ng th\u1ee9c semaglutide \u0111\u01b0\u1ee3c b\u00e1n tr\u00ean th\u1ecb tr\u01b0\u1eddng. Semaglutide \u0111\u00e3 \u0111\u01b0\u1ee3c th\u1eed nghi\u1ec7m trong c\u00e1c nghi\u00ean c\u1ee9u b\u1eb1ng ch\u1ee9ng th\u1ef1c t\u1ebf, quy m\u00f4 l\u1edbn v\u00e0 c\u00e1c ch\u01b0\u01a1ng tr\u00ecnh ph\u00e1t tri\u1ec3n l\u00e2m s\u00e0ng m\u1ea1nh m\u1ebd v\u1edbi m\u1ee9c ph\u01a1i nhi\u1ec5m t\u00edch l\u0169y tr\u00ean 12 tri\u1ec7u b\u1ec7nh nh\u00e2n\/n\u0103m. T\u1ed5ng s\u1ed1 d\u1eef li\u1ec7u mang l\u1ea1i s\u1ef1 y\u00ean t\u00e2m cho k\u1ebft qu\u1ea3 h\u1ed3 s\u01a1 an to\u00e0n c\u1ee7a semaglutide.\u201d<\/p>\n
Thu\u1ed1c gi\u1ea3m c\u00e2n Wegovy ch\u1eefa b\u1ec7nh b\u00e9o ph\u00ec. (H\u00ecnh minh h\u1ecda: Michael Siluk\/UCG\/Universal Images Group via Getty Images)<\/p>\n
Semaglutide hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c ki\u1ec3m tra trong m\u1ed9t th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng do Novo Nordisk th\u1ef1c hi\u1ec7n \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 t\u00e1c d\u1ee5ng l\u00e2u d\u00e0i c\u1ee7a semaglutide 1mg \u0111\u1ed1i v\u1edbi b\u1ec7nh v\u00f5ng m\u1ea1c ti\u1ec3u \u0111\u01b0\u1eddng \u1edf b\u1ec7nh nh\u00e2n ti\u1ec3u \u0111\u01b0\u1eddng Lo\u1ea1i Hai v\u1edbi th\u1eddi gian ho\u00e0n th\u00e0nh d\u1ef1 ki\u1ebfn v\u00e0o n\u0103m 2027.<\/p>\n
C\u00f4ng ty d\u01b0\u1ee3c ph\u1ea9m c\u1ee7a \u0110an M\u1ea1ch n\u00f3i th\u00eam r\u1eb1ng c\u00f3 nh\u1eefng h\u1ea1n ch\u1ebf ch\u00ednh v\u1ec1 \u0111o l\u01b0\u1eddng trong kh\u00e1m ph\u00e1, c\u1ea7n \u0111\u01b0\u1ee3c xem x\u00e9t khi di\u1ec5n gi\u1ea3i c\u00e1c ph\u00e1t hi\u1ec7n.<\/p>\n
V\u00ed d\u1ee5 nh\u01b0 nghi\u00ean c\u1ee9u kh\u00f4ng cung c\u1ea5p th\u00f4ng tin v\u1ec1 li\u1ec1u semaglutide khi b\u1eaft \u0111\u1ea7u v\u00e0 k\u1ebft th\u00fac \u0111i\u1ec1u tr\u1ecb. Ngo\u00e0i ra, c\u00e1c y\u1ebfu t\u1ed1 g\u00e2y nhi\u1ec5u nh\u01b0 h\u00fat thu\u1ed1c, th\u1eddi gian m\u1eafc b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng v\u00e0 h\u00ecnh th\u00e1i \u0111\u0129a quang kh\u00f4ng \u0111\u01b0\u1ee3c xem x\u00e9t trong ph\u00e2n t\u00edch.<\/p>\n
Margaret Morris, gi\u00e1o s\u01b0 d\u01b0\u1ee3c l\u00fd c\u1ee7a Tr\u01b0\u1eddng Khoa H\u1ecdc Y Sinh t\u1ea1i University of New South Wales c\u1ee7a \u00dac, cho bi\u1ebft trong m\u1ed9t tuy\u00ean b\u1ed1: \u201c\u0110\u00e2y l\u00e0 m\u1ed9t b\u00e1o c\u00e1o th\u00fa v\u1ecb v\u1ec1 h\u1eadu qu\u1ea3 ti\u00eau c\u1ef1c ti\u1ec1m \u1ea9n c\u1ee7a vi\u1ec7c k\u00ea \u0111\u01a1n thu\u1ed1c ch\u1ee7 v\u1eadn GLP-1 semaglutide cho nh\u1eefng ng\u01b0\u1eddi m\u1eafc b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng, \u0111\u1ed1i v\u1edbi nguy c\u01a1 NAION, m\u1ed9t nguy\u00ean nh\u00e2n g\u00e2y m\u00f9 l\u00f2a. So v\u1edbi nh\u1eefng lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c k\u00ea toa kh\u00e1c cho b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng, nh\u1eefng ng\u01b0\u1eddi d\u00f9ng semaglutide c\u00f3 nguy c\u01a1 m\u1eafc NAION cao h\u01a1n sau ba n\u0103m. C\u00e1c t\u00e1c gi\u1ea3 \u0111\u01b0a ra c\u1ea3nh b\u00e1o r\u1eb1ng thu\u1ed1c c\u00f3 kh\u1ea3 n\u0103ng l\u00e0m t\u0103ng nguy c\u01a1 m\u1eafc b\u1ec7nh n\u00e0y, \u0111\u1ed3ng th\u1eddi ch\u1ec9 ra r\u1eb1ng c\u1ea7n ph\u1ea3i nghi\u00ean c\u1ee9u th\u00eam \u0111\u1ec3 x\u00e1c nh\u1eadn b\u1ea5t k\u1ef3 m\u1ed1i li\u00ean quan n\u00e0o. \u0110\u00e1ng ch\u00fa \u00fd l\u00e0 nh\u00f3m \u0111\u01b0\u1ee3c k\u00ea \u0111\u01a1n semaglutide c\u00f3 tu\u1ed5i \u0111\u1eddi cao h\u01a1n nh\u00f3m c\u00f2n l\u1ea1i, nh\u01b0ng c\u00e1c t\u00e1c gi\u1ea3 cho r\u1eb1ng nguy c\u01a1 kh\u00f4ng li\u00ean quan \u0111\u1ebfn nh\u1eefng kh\u00e1c bi\u1ec7t c\u01a1 b\u1ea3n.\u201d<\/p>\n
M\u1eb7c d\u00f9 c\u00e1c nh\u00e0 khoa h\u1ecdc th\u1eeba nh\u1eadn nh\u1eefng ph\u00e1t hi\u1ec7n n\u00e0y kh\u00f4ng cho th\u1ea5y semaglutide l\u00e0 nguy\u00ean nh\u00e2n l\u00e0m t\u0103ng nguy c\u01a1 n\u00e0y, nh\u01b0ng h\u1ecd nh\u1ea5n m\u1ea1nh c\u1ea7n ph\u1ea3i nghi\u00ean c\u1ee9u s\u00e2u h\u01a1n \u0111\u1ec3 hi\u1ec3u r\u00f5 h\u01a1n v\u1ec1 m\u1ed1i t\u01b0\u01a1ng quan.<\/p>\n
The post Thu\u1ed1c gi\u1ea3m c\u00e2n l\u00e0m t\u0103ng nguy c\u01a1 b\u1ec7nh g\u00e2y m\u00f9 l\u00f2a hi\u1ebfm g\u1eb7p<\/a> appeared first on Saigon Nh\u1ecf<\/a>.<\/p>\n \u00a0<\/p>","protected":false},"excerpt":{"rendered":" M\u1ed9t nghi\u00ean c\u1ee9u m\u1edbi cho th\u1ea5y Semaglutide, th\u00e0nh ph\u1ea7n ho\u1ea1t ch\u1ea5t trong thu\u1ed1c gi\u1ea3m c\u00e2n Ozempic v\u00e0 Wegovy, c\u00f3 li\u00ean quan \u0111\u1ebfn vi\u1ec7c t\u0103ng nguy c\u01a1 m\u1eafc c\u00e1c b\u1ec7nh v\u1ec1 m\u1eaft g\u00e2y gi\u1ea3m th\u1ecb l\u1ef1c. C\u00e1c nh\u00e0 khoa h\u1ecdc t\u1ea1i tr\u01b0\u1eddng Harvard School of Public Health ch\u1ec9 ra m\u1ed1i li\u00ean h\u1ec7 gi\u1eefa Ozempic v\u00e0 kh\u1ea3 …<\/p>","protected":false},"author":0,"featured_media":51980,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[82,43],"tags":[],"class_list":["post-51979","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-society","category-health"],"_links":{"self":[{"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/posts\/51979","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/comments?post=51979"}],"version-history":[{"count":0,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/posts\/51979\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/media\/51980"}],"wp:attachment":[{"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/media?parent=51979"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/categories?post=51979"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/tags?post=51979"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}