S\u1ed1 l\u1ea7n m\u1ed9t ng\u01b0\u1eddi \u0111i ti\u00eau trong v\u00f2ng 24 gi\u1edd l\u00e0 d\u1ea5u hi\u1ec7u quan tr\u1ecdng cho th\u1ea5y ng\u01b0\u1eddi n\u00e0y kh\u1ecfe m\u1ea1nh hay y\u1ebfu.<\/p>\n
Theo m\u1ed9t b\u00e0i b\u00e1o m\u1edbi tr\u00ean t\u1ea1p ch\u00ed Cell Reports Medicine, t\u1ea7n su\u1ea5t \u0111i ti\u00eau c\u1ee7a m\u1ed9t ng\u01b0\u1eddi c\u00f3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ee9c kh\u1ecfe c\u1ee7a h\u1ecd do t\u00e1c \u0111\u1ed9ng c\u1ee7a vi\u1ec7c \u0111\u1ea1i ti\u1ec7n l\u00ean h\u1ec7 vi sinh v\u1eadt \u0111\u01b0\u1eddng ru\u1ed9t.<\/p>\n
C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u ph\u00e1t hi\u1ec7n ra r\u1eb1ng \u0111i \u0111\u1ea1i ti\u1ec7n m\u1ed9t \u0111\u1ebfn hai l\u1ea7n m\u1ed9t ng\u00e0y l\u00e0 \u201cv\u00f9ng Goldilocks\u201d \u0111\u1ed1i v\u1edbi s\u1ee9c kh\u1ecfe. \u0110\u1ed3ng t\u00e1c gi\u1ea3 c\u1ee7a th\u1eed nghi\u1ec7m \u2013 Sean Gibbons, ph\u00f3 gi\u00e1o s\u01b0 t\u1ea1i Vi\u1ec7n Sinh H\u1ecdc H\u1ec7 Th\u1ed1ng (Institute for Systems Biology \u2013 ISB), cho bi\u1ebft ph\u00e1t hi\u1ec7n n\u00e0y cho th\u1ea5y t\u1ea7n su\u1ea5t \u0111i ti\u00eau c\u00f3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn t\u1ea5t c\u1ea3 c\u00e1c h\u1ec7 th\u1ed1ng c\u01a1 th\u1ec3 nh\u01b0 th\u1ebf n\u00e0o v\u00e0 s\u1ed1 l\u1ea7n \u0111i ti\u00eau b\u1ea5t th\u01b0\u1eddng l\u00e0 m\u1ed9t y\u1ebfu t\u1ed1 c\u1ea7n l\u01b0u \u00fd trong s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a c\u00e1c b\u1ec7nh m\u00e3n t\u00ednh.<\/p>\n
Trong b\u00e0i b\u00e1o, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u m\u00f4 t\u1ea3 c\u00e1ch h\u1ecd ph\u00e2n t\u00edch d\u1eef li\u1ec7u t\u1eeb h\u01a1n 1,400 ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh v\u1ec1 l\u1ed1i s\u1ed1ng, ti\u1ec1n s\u1eed b\u1ec7nh v\u00e0 t\u1ea7n su\u1ea5t \u0111i \u0111\u1ea1i ti\u1ec7n. H\u1ecd ph\u00e1t hi\u1ec7n ra r\u1eb1ng c\u00f3 b\u1ed1n lo\u1ea1i khi n\u00f3i \u0111\u1ebfn nhu \u0111\u1ed9ng ru\u1ed9t: m\u1ed9t \u0111\u1ebfn hai l\u1ea7n m\u1ed7i tu\u1ea7n (t\u00e1o b\u00f3n), ba \u0111\u1ebfn s\u00e1u l\u1ea7n m\u1ed7i tu\u1ea7n (\u00edt nh\u01b0ng v\u1eabn b\u00ecnh th\u01b0\u1eddng), m\u1ed9t \u0111\u1ebfn ba l\u1ea7n m\u1ed7i ng\u00e0y (nhi\u1ec1u nh\u01b0ng c\u0169ng b\u00ecnh th\u01b0\u1eddng) v\u00e0 ti\u00eau ch\u1ea3y.<\/p>\n
C\u00e1c nh\u00e0 khoa h\u1ecdc ph\u00e1t hi\u1ec7n ra r\u1eb1ng nh\u1eefng ng\u01b0\u1eddi tr\u1ebb tu\u1ed5i, ph\u1ee5 n\u1eef v\u00e0 nh\u1eefng ng\u01b0\u1eddi c\u00f3 Ch\u1ec9 S\u1ed1 Kh\u1ed1i C\u01a1 Th\u1ec3 (Body Mass Index \u2013 BMI) th\u1ea5p, c\u00f3 xu h\u01b0\u1edbng \u0111i \u0111\u1ea1i ti\u1ec7n \u00edt th\u01b0\u1eddng xuy\u00ean h\u01a1n.<\/p>\n
\u0110\u1ed3ng t\u00e1c gi\u1ea3 Johannes Johnson-Martinez, c\u0169ng l\u00e0 nh\u00e0 nghi\u00ean c\u1ee9u t\u1ea1i ISB, chia s\u1ebb trong tuy\u00ean b\u1ed1: \u201cPh\u00e1t hi\u1ec7n tr\u01b0\u1edbc \u0111\u00e2y ch\u1ec9 ra r\u1eb1ng t\u1ea7n su\u1ea5t \u0111i ti\u00eau c\u00f3 th\u1ec3 c\u00f3 t\u00e1c \u0111\u1ed9ng l\u1edbn \u0111\u1ebfn ch\u1ee9c n\u0103ng h\u1ec7 sinh th\u00e1i \u0111\u01b0\u1eddng ru\u1ed9t. \u0110\u1eb7c bi\u1ec7t, n\u1ebfu ph\u00e2n t\u1ed3n t\u1ea1i qu\u00e1 l\u00e2u trong ru\u1ed9t, vi khu\u1ea9n s\u1ebd s\u1eed d\u1ee5ng h\u1ebft ch\u1ea5t x\u01a1 c\u00f3 s\u1eb5n \u0111\u1ec3 l\u00ean men th\u00e0nh c\u00e1c acid b\u00e9o chu\u1ed7i ng\u1eafn c\u00f3 l\u1ee3i. Sau \u0111\u00f3, h\u1ec7 sinh th\u00e1i chuy\u1ec3n sang qu\u00e1 tr\u00ecnh l\u00ean men protein, t\u1ea1o ra m\u1ed9t s\u1ed1 ch\u1ea5t \u0111\u1ed9c c\u00f3 kh\u1ea3 n\u0103ng x\u00e2m nh\u1eadp v\u00e0o m\u00e1u.\u201d<\/p>\n
H\u1ecd c\u0169ng ph\u00e1t hi\u1ec7n ra m\u1ed1i li\u00ean h\u1ec7 gi\u1eefa h\u1ec7 vi sinh v\u1eadt \u0111\u01b0\u1eddng ru\u1ed9t c\u1ee7a nh\u1eefng ng\u01b0\u1eddi tham gia v\u00e0 s\u1ed1 l\u1ea7n h\u1ecd \u0111i ti\u00eau v\u1edbi vi khu\u1ea9n \u0111\u01b0\u1eddng ru\u1ed9t l\u00ean men ch\u1ea5t x\u01a1 c\u00f3 li\u00ean quan \u0111\u1ebfn s\u1ee9c kh\u1ecfe. Nh\u1eefng vi khu\u1ea9n n\u00e0y d\u01b0\u1eddng nh\u01b0 hi\u1ec7n di\u1ec7n v\u1edbi s\u1ed1 l\u01b0\u1ee3ng l\u1edbn \u1edf nh\u1eefng ng\u01b0\u1eddi n\u1eb1m trong v\u00f9ng Goldilocks \u0111i \u0111\u1ea1i ti\u1ec7n t\u1eeb m\u1ed9t \u0111\u1ebfn hai l\u1ea7n m\u1ed7i ng\u00e0y. Thay v\u00e0o \u0111\u00f3, nh\u1eefng ng\u01b0\u1eddi b\u1ecb t\u00e1o b\u00f3n ho\u1eb7c ti\u00eau ch\u1ea3y c\u00f3 xu h\u01b0\u1edbng c\u00f3 vi khu\u1ea9n li\u00ean quan \u0111\u1ebfn qu\u00e1 tr\u00ecnh l\u00ean men protein ho\u1eb7c \u0111\u01b0\u1eddng ti\u00eau h\u00f3a tr\u00ean.<\/p>\n
Ngo\u00e0i ra, c\u00e1c nh\u00e0 khoa h\u1ecdc c\u00f2n t\u00ecm th\u1ea5y m\u1ed1i t\u01b0\u01a1ng quan gi\u1eefa t\u1ea7n su\u1ea5t \u0111i ti\u00eau v\u00e0 c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a trong m\u00e1u, cho th\u1ea5y m\u1ed1i li\u00ean h\u1ec7 gi\u1eefa nguy c\u01a1 m\u1eafc b\u1ec7nh m\u00e3n t\u00ednh v\u00e0 t\u1ea7n su\u1ea5t \u0111\u1ea1i ti\u1ec7n. Nh\u1eefng ng\u01b0\u1eddi b\u1ecb t\u00e1o b\u00f3n c\u00f3 h\u00e0m l\u01b0\u1ee3ng p-cresol-sulfate v\u00e0 indoxyl-sulfate cao h\u01a1n, c\u00f3 th\u1ec3 g\u00e2y h\u1ea1i cho th\u1eadn v\u00e0 \u0111\u01b0\u1ee3c t\u1ea1o ra b\u1edfi qu\u00e1 tr\u00ecnh l\u00ean men protein c\u1ee7a vi khu\u1ea9n. Nh\u1eefng ng\u01b0\u1eddi b\u1ecb ti\u00eau ch\u1ea3y c\u00f3 c\u00e1c h\u1ee3p ch\u1ea5t li\u00ean quan \u0111\u1ebfn t\u1ed5n th\u01b0\u01a1ng gan.<\/p>\n
B\u00e1c S\u0129 Sean Gibbons, t\u00e1c gi\u1ea3 t\u01b0\u01a1ng \u1ee9ng c\u1ee7a b\u00e0i b\u00e1o, cho bi\u1ebft: \u201cT\u00e1o b\u00f3n m\u00e3n t\u00ednh c\u00f3 li\u00ean quan \u0111\u1ebfn r\u1ed1i lo\u1ea1n tho\u00e1i h\u00f3a th\u1ea7n kinh v\u00e0 ti\u1ebfn tri\u1ec3n b\u1ec7nh th\u1eadn m\u00e3n t\u00ednh \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh \u0111ang ho\u1ea1t \u0111\u1ed9ng. Tuy nhi\u00ean, v\u1eabn ch\u01b0a r\u00f5 li\u1ec7u nh\u1eefng b\u1ea5t th\u01b0\u1eddng trong nhu \u0111\u1ed9ng ru\u1ed9t c\u00f3 ph\u1ea3i l\u00e0 nguy\u00ean nh\u00e2n ban \u0111\u1ea7u g\u00e2y ra b\u1ec7nh m\u00e3n t\u00ednh v\u00e0 t\u1ed5n th\u01b0\u01a1ng n\u1ed9i t\u1ea1ng hay kh\u00f4ng, hay li\u1ec7u nh\u1eefng m\u1ed1i li\u00ean h\u1ec7 h\u1ed3i c\u1ee9u n\u00e0y \u1edf b\u1ec7nh nh\u00e2n b\u1ecb b\u1ec7nh ch\u1ec9 l\u00e0 s\u1ef1 tr\u00f9ng h\u1ee3p ng\u1eabu nhi\u00ean. \u1ede \u0111\u00e2y, trong m\u1ed9t nh\u00f3m d\u00e2n s\u1ed1 kh\u1ecfe m\u1ea1nh n\u00f3i chung, ch\u00fang t\u00f4i th\u1ea5y r\u1eb1ng t\u00e1o b\u00f3n n\u00f3i ri\u00eang c\u00f3 li\u00ean quan \u0111\u1ebfn n\u1ed3ng \u0111\u1ed9 ch\u1ea5t \u0111\u1ed9c c\u00f3 ngu\u1ed3n g\u1ed1c t\u1eeb vi khu\u1ea9n trong m\u00e1u \u0111\u01b0\u1ee3c bi\u1ebft l\u00e0 g\u00e2y t\u1ed5n th\u01b0\u01a1ng n\u1ed9i t\u1ea1ng, tr\u01b0\u1edbc khi \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n b\u1ec7nh.\u201d<\/p>\n
C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u l\u01b0u \u00fd r\u1eb1ng \u0103n nhi\u1ec1u ch\u1ea5t x\u01a1, u\u1ed1ng \u0111\u1ea7y \u0111\u1ee7 n\u01b0\u1edbc v\u00e0 t\u1eadp th\u1ec3 d\u1ee5c th\u01b0\u1eddng xuy\u00ean \u0111\u00e3 gi\u00fap m\u1ecdi ng\u01b0\u1eddi duy tr\u00ec v\u00f9ng Goldilocks.<\/p>\n
Gibbons k\u1ebft lu\u1eadn: \u201cNh\u1eefng hi\u1ec3u bi\u1ebft s\u00e2u s\u1eafc n\u00e0y cung c\u1ea5p c\u00e1c chi\u1ebfn l\u01b0\u1ee3c \u0111\u1ec3 qu\u1ea3n l\u00fd t\u1ea7n su\u1ea5t \u0111i \u0111\u1ea1i ti\u1ec7n, ngay c\u1ea3 \u1edf nh\u1eefng ng\u01b0\u1eddi kh\u1ecfe m\u1ea1nh, nh\u1eb1m t\u1ed1i \u01b0u h\u00f3a s\u1ee9c kh\u1ecfe v\u00e0 th\u1ec3 tr\u1ea1ng.\u201d<\/p>\n
The post S\u1ed1 l\u1ea7n \u0111i \u0111\u1ea1i ti\u1ec7n n\u00f3i l\u00ean s\u1ee9c kh\u1ecfe c\u1ee7a b\u1ea1n<\/a> appeared first on Saigon Nh\u1ecf<\/a>.<\/p>\n \u00a0<\/p>","protected":false},"excerpt":{"rendered":" S\u1ed1 l\u1ea7n m\u1ed9t ng\u01b0\u1eddi \u0111i ti\u00eau trong v\u00f2ng 24 gi\u1edd l\u00e0 d\u1ea5u hi\u1ec7u quan tr\u1ecdng cho th\u1ea5y ng\u01b0\u1eddi n\u00e0y kh\u1ecfe m\u1ea1nh hay y\u1ebfu. Theo m\u1ed9t b\u00e0i b\u00e1o m\u1edbi tr\u00ean t\u1ea1p ch\u00ed Cell Reports Medicine, t\u1ea7n su\u1ea5t \u0111i ti\u00eau c\u1ee7a m\u1ed9t ng\u01b0\u1eddi c\u00f3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ee9c kh\u1ecfe c\u1ee7a h\u1ecd do t\u00e1c \u0111\u1ed9ng c\u1ee7a vi\u1ec7c \u0111\u1ea1i …<\/p>","protected":false},"author":0,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[82,43],"tags":[],"class_list":["post-52272","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-society","category-health"],"_links":{"self":[{"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/posts\/52272","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/comments?post=52272"}],"version-history":[{"count":0,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/posts\/52272\/revisions"}],"wp:attachment":[{"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/media?parent=52272"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/categories?post=52272"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/tags?post=52272"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}