Khi m\u1ed9t bu\u1ed5i t\u1ed1i th\u01b0 gi\u00e3n v\u1edbi m\u1ed9t ly r\u01b0\u1ee3u vang \u0111\u1ecf bi\u1ebfn th\u00e0nh c\u01a1n \u0111au \u0111\u1ea7u d\u1eef d\u1ed9i, \u0111i\u1ec1u \u0111\u00f3 t\u1ea5t nhi\u00ean s\u1ebd g\u00e2y kh\u00f3 ch\u1ecbu. \u0110\u1ed1i v\u1edbi h\u00e0ng tri\u1ec7u ng\u01b0\u1eddi, \u0111\u00e2y l\u00e0 m\u1ed9t v\u1ea5n \u0111\u1ec1 r\u1ea5t th\u1ef1c t\u1ebf v\u00e0 c\u00e1c nh\u00e0 khoa h\u1ecdc cu\u1ed1i c\u00f9ng c\u0169ng b\u1eaft \u0111\u1ea7u v\u00e0o cu\u1ed9c. H\u00f3a ra, th\u1ee7 ph\u1ea1m \u0111\u1eb1ng sau nh\u1eefng c\u01a1n \u0111au \u0111\u1ea7u do r\u01b0\u1ee3u vang \u0111\u1ecf n\u1eb1m \u1edf ch\u00ednh nh\u1eefng qu\u1ea3 nho.<\/p>\n
Trong m\u1ed9t th\u1eddi gian d\u00e0i, c\u00e1c l\u00fd thuy\u1ebft h\u00e0ng \u0111\u1ea7u v\u1ec1 ch\u1ee9ng \u0111au \u0111\u1ea7u do r\u01b0\u1ee3u vang \u0111\u1ecf t\u1eadp trung v\u00e0o sulfite, histamine ho\u1eb7c\u00a0tannin. M\u1eb7c d\u00f9 nh\u1eefng h\u1ee3p ch\u1ea5t n\u00e0y g\u00e2y ra ph\u1ea3n \u1ee9ng ph\u1ee5 \u1edf m\u1ed9t s\u1ed1 ng\u01b0\u1eddi, nh\u01b0ng kh\u00f4ng gi\u1ea3i th\u00edch \u0111\u1ea7y \u0111\u1ee7 t\u1ea1i sao r\u01b0\u1ee3u vang \u0111\u1ecf n\u00f3i ri\u00eang d\u01b0\u1eddng nh\u01b0 g\u00e2y \u0111au \u0111\u1ea7u nhi\u1ec1u h\u01a1n c\u00e1c lo\u1ea1i \u0111\u1ed3 u\u1ed1ng c\u00f3 c\u1ed3n kh\u00e1c.<\/p>\n
M\u1ed9t nghi\u00ean c\u1ee9u m\u1edbi mang t\u00ednh \u0111\u1ed9t ph\u00e1 t\u1eeb \u0111\u1ea1i h\u1ecdc University of California, Davis (UC Davis) \u0111\u01b0a ra m\u1ed9t l\u1eddi gi\u1ea3i \u0111\u00e1p thuy\u1ebft ph\u1ee5c kh\u00e1c. \u0110\u01b0\u1ee3c c\u00f4ng b\u1ed1 tr\u00ean Scientific Reports, nghi\u00ean c\u1ee9u ch\u1ec9 ra m\u1ed9t h\u1ee3p ch\u1ea5t c\u1ee5 th\u1ec3 \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong r\u01b0\u1ee3u vang \u0111\u1ecf: quercetin.<\/p>\n
Quercetin l\u00e0 g\u00ec v\u00e0 n\u00f3 g\u00e2y \u0111au \u0111\u1ea7u nh\u01b0 th\u1ebf n\u00e0o?<\/p>\n
Quercetin l\u00e0 m\u1ed9t lo\u1ea1i flavanol, m\u1ed9t nh\u00f3m c\u00e1c h\u1ee3p ch\u1ea5t c\u00f3 ngu\u1ed3n g\u1ed1c th\u1ef1c v\u1eadt \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn v\u1edbi \u0111\u1eb7c t\u00ednh ch\u1ed1ng oxy h\u00f3a. Quercetin c\u00f3 s\u1eb5n trong nhi\u1ec1u lo\u1ea1i tr\u00e1i c\u00e2y v\u00e0 rau qu\u1ea3, nh\u01b0 h\u00e0nh t\u00e2y, t\u00e1o v\u00e0 c\u00e1c lo\u1ea1i qu\u1ea3 m\u1ecdng v\u00e0 th\u01b0\u1eddng c\u00f3 l\u1ee3i cho s\u1ee9c kh\u1ecfe. Tuy nhi\u00ean, trong b\u1ed1i c\u1ea3nh r\u01b0\u1ee3u vang \u0111\u1ecf, quercetin c\u0169ng d\u1eabn \u0111\u1ebfn\u00a0m\u1ed9t lo\u1ea1t c\u00e1c ph\u1ea3n \u1ee9ng\u00a0l\u00e0m \u0111au \u0111\u1ea7u.<\/p>\n
C\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng nh\u01b0 sau: Khi b\u1ea1n u\u1ed1ng r\u01b0\u1ee3u vang \u0111\u1ecf, quercetin trong r\u01b0\u1ee3u s\u1ebd \u0111\u01b0\u1ee3c c\u01a1 th\u1ec3 chuy\u1ec3n h\u00f3a th\u00e0nh m\u1ed9t h\u1ee3p ch\u1ea5t kh\u00e1c g\u1ecdi l\u00e0 quercetin glucuronide. C\u00e1c nh\u00e0 khoa h\u1ecdc tin h\u1ee3p ch\u1ea5t m\u1edbi n\u00e0y ch\u00ednh l\u00e0 th\u1ee7 ph\u1ea1m g\u00e2y ra v\u1ea5n \u0111\u1ec1. Quercetin glucuronide \u0111\u01b0\u1ee3c ch\u1ee9ng minh c\u00f3 th\u1ec3 can thi\u1ec7p v\u00e0o ch\u1ee9c n\u0103ng c\u1ee7a m\u1ed9t enzyme quan tr\u1ecdng trong qu\u00e1 tr\u00ecnh trao \u0111\u1ed5i ch\u1ea5t c\u1ee7a c\u01a1 th\u1ec3, \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 aldehyde dehydrogenase 2 (ALDH2).<\/p>\n
Nhi\u1ec7m v\u1ee5 c\u1ee7a enzyme ALDH2 l\u00e0 ph\u00e2n h\u1ee7y m\u1ed9t ch\u1ea5t \u0111\u1ed9c h\u1ea1i, acetaldehyde, \u0111\u01b0\u1ee3c s\u1ea3n sinh ra khi c\u01a1 th\u1ec3 b\u1ea1n x\u1eed l\u00fd r\u01b0\u1ee3u. Acetaldehyde l\u00e0 m\u1ed9t ch\u1ea5t \u0111\u1ed9c n\u1ed5i ti\u1ebfng v\u1edbi nguy c\u01a1 l\u00e0m\u00a0\u0111\u1ecf b\u1eebng m\u1eb7t, bu\u1ed3n n\u00f4n v\u00e0 \u0111\u00e1ng ch\u00fa \u00fd nh\u1ea5t, \u0111au \u0111\u1ea7u. Khi quercetin glucuronide t\u1eeb r\u01b0\u1ee3u vang \u0111\u1ecf \u1ee9c ch\u1ebf enzyme ALDH2, acetaldehyde s\u1ebd t\u00edch t\u1ee5 trong c\u01a1 th\u1ec3, d\u1eabn \u0111\u1ebfn nh\u1eefng tri\u1ec7u ch\u1ee9ng kh\u00f3 ch\u1ecbu n\u00e0y. H\u00e3y t\u01b0\u1edfng t\u01b0\u1ee3ng t\u00ecnh tr\u1ea1ng n\u00e0y gi\u1ed1ng nh\u01b0 t\u1eafc \u0111\u01b0\u1eddng tr\u00ean cao t\u1ed1c \u2013 quercetin glucuronide ng\u0103n ch\u1eb7n enzyme \u0111\u01b0\u1ee3c cho l\u00e0 c\u00f3 ch\u1ee9c n\u0103ng lo\u1ea1i b\u1ecf acetaldehyde, g\u00e2y ra s\u1ef1 t\u00edch t\u1ee5 h\u1ee3p ch\u1ea5t \u0111\u1ed9c h\u1ea1i v\u00e0 t\u1ea1o th\u00e0nh\u00a0c\u01a1n \u0111au \u0111\u1ea7u d\u1eef d\u1ed9i.<\/p>\n
T\u1ea1i sao n\u00f3 ch\u1ec9 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn m\u1ed9t s\u1ed1 ng\u01b0\u1eddi?<\/p>\n
\u0110i\u1ec1u n\u00e0y \u0111\u01b0a ch\u00fang ta \u0111\u1ebfn m\u1ed9t c\u00e2u h\u1ecfi quan tr\u1ecdng: N\u1ebfu quercetin c\u00f3 trong t\u1ea5t c\u1ea3 c\u00e1c lo\u1ea1i r\u01b0\u1ee3u vang \u0111\u1ecf, t\u1ea1i sao ch\u1ec9 m\u1ed9t s\u1ed1 ng\u01b0\u1eddi b\u1ecb \u0111au \u0111\u1ea7u? C\u00e2u tr\u1ea3 l\u1eddi n\u1eb1m \u1edf di truy\u1ec1n. Kho\u1ea3ng 8% d\u00e2n s\u1ed1 to\u00e0n c\u1ea7u b\u1ecb thi\u1ebfu enzyme ALDH2. S\u1ef1 thi\u1ebfu h\u1ee5t n\u00e0y ph\u1ed5 bi\u1ebfn \u1edf nh\u1eefng ng\u01b0\u1eddi g\u1ed1c \u0110\u00f4ng \u00c1 \u2013 l\u00fd do t\u1ea1i sao t\u00ecnh tr\u1ea1ng \u0111\u00f4i khi \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 \u201ch\u1ed3ng ban ch\u00e2u \u00c1\u201d l\u1ea1i ph\u1ed5 bi\u1ebfn \u0111\u1ebfn v\u1eady. Khi m\u1ed9t ng\u01b0\u1eddi c\u00f3 l\u01b0\u1ee3ng ALDH2 t\u1ef1 nhi\u00ean th\u1ea5p u\u1ed1ng r\u01b0\u1ee3u vang \u0111\u1ecf, quercetin ch\u1ec9 l\u00e0m cho v\u1ea5n \u0111\u1ec1 tr\u1edf n\u00ean t\u1ed3i t\u1ec7 th\u00eam, d\u1eabn \u0111\u1ebfn s\u1ef1 t\u00edch t\u1ee5 acetaldehyde nhanh v\u00e0 nghi\u00eam tr\u1ecdng.<\/p>\n
Tuy nhi\u00ean, ngay c\u1ea3 v\u1edbi nh\u1eefng ng\u01b0\u1eddi kh\u00f4ng b\u1ecb thi\u1ebfu h\u1ee5t gen v\u1eabn c\u00f3 m\u1ed9t lo\u1ea1t c\u00e1c nh\u1ea1y c\u1ea3m. C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u cho r\u1eb1ng l\u01b0\u1ee3ng quercetin trong m\u1ed9t lo\u1ea1i r\u01b0\u1ee3u vang c\u1ee5 th\u1ec3 c\u0169ng \u0111\u00f3ng m\u1ed9t vai tr\u00f2 quan tr\u1ecdng. Th\u00fa v\u1ecb thay, h\u00e0m l\u01b0\u1ee3ng quercetin trong nho c\u00f3 li\u00ean quan tr\u1ef1c ti\u1ebfp \u0111\u1ebfn vi\u1ec7c ti\u1ebfp x\u00fac v\u1edbi \u00e1nh n\u1eafng m\u1eb7t tr\u1eddi. Nho \u0111\u01b0\u1ee3c tr\u1ed3ng \u1edf nh\u1eefng v\u01b0\u1eddn nho nhi\u1ec1u n\u1eafng ho\u1eb7c tr\u00ean nh\u1eefng c\u00e2y nho ti\u1ebfp x\u00fac nhi\u1ec1u v\u1edbi \u00e1nh n\u1eafng m\u1eb7t tr\u1eddi th\u01b0\u1eddng c\u00f3 n\u1ed3ng \u0111\u1ed9 flavanol n\u00e0y kh\u00e1 cao. Do \u0111\u00f3, m\u1ed9t lo\u1ea1i r\u01b0\u1ee3u vang Cabernet Sauvignon \u0111\u1eadm \u0111\u00e0, th\u01a1m ngon t\u1eeb v\u00f9ng n\u1eafng s\u1ebd d\u1ec5 g\u00e2y \u0111au \u0111\u1ea7u h\u01a1n m\u1ed9t lo\u1ea1i r\u01b0\u1ee3u vang Pinot Noir nh\u1eb9 t\u1eeb v\u00f9ng kh\u00ed h\u1eadu m\u00e1t m\u1ebb.<\/p>\n
L\u01b0u \u00fd th\u00eam r\u1eb1ng\u00a0hi\u1ec7n t\u1ea1i, gi\u1ea3 thuy\u1ebft v\u1ec1 quercetin v\u1eabn l\u00e0 m\u1ed9t l\u0129nh v\u1ef1c nghi\u00ean c\u1ee9u m\u1edbi v\u00e0 \u0111ang ph\u00e1t tri\u1ec3n. Nh\u00f3m nghi\u00ean c\u1ee9u t\u1ea1i UC Davis \u0111ang c\u00f3 k\u1ebf ho\u1ea1ch ti\u1ebfn h\u00e0nh m\u1ed9t th\u1eed nghi\u1ec7m tr\u00ean ng\u01b0\u1eddi quy m\u00f4 nh\u1ecf \u0111\u1ec3 t\u00ecm hi\u1ec3u s\u00e2u xa v\u1ec1 nh\u1eefng ph\u00e1t hi\u1ec7n c\u1ee7a h\u1ecd v\u00e0 c\u1ee7ng c\u1ed1 m\u1ed1i li\u00ean h\u1ec7 gi\u1eefa h\u00e0m l\u01b0\u1ee3ng quercetin trong r\u01b0\u1ee3u vang v\u00e0 c\u00e1c tri\u1ec7u ch\u1ee9ng \u0111au \u0111\u1ea7u.<\/p>\n
N\u1ebfu b\u1ea1n l\u00e0 ng\u01b0\u1eddi th\u01b0\u1eddng xuy\u00ean b\u1ecb nh\u1ee9c\u00a0\u0111\u1ea7u sau khi u\u1ed1ng r\u01b0\u1ee3u vang \u0111\u1ecf, h\u00e3y xem nghi\u00ean c\u1ee9u n\u00e0y nh\u01b0 m\u1ed9t m\u1ed9t l\u00fd do thuy\u1ebft ph\u1ee5c \u0111\u1ec3 th\u1eed m\u1ed9t th\u1ee9c u\u1ed1ng kh\u00e1c. Trong khi r\u01b0\u1ee3u vang \u0111\u1ecf ch\u1ee9a nhi\u1ec1u quercetin, r\u01b0\u1ee3u vang tr\u1eafng th\u01b0\u1eddng ch\u1ee9a \u00edt flavanol, khi\u1ebfn n\u00f3 tr\u1edf th\u00e0nh m\u1ed9t l\u1ef1a ch\u1ecdn an to\u00e0n cho b\u1ea1n.<\/p>\n
L\u1ea7n t\u1edbi khi b\u1ea1n \u0111i mua s\u1eafm ho\u1eb7c \u0103n t\u1ea1i nh\u00e0 h\u00e0ng, h\u00e3y th\u1eed chuy\u1ec3n sang u\u1ed1ng m\u1ed9t ly Sauvignon Blanc thanh m\u00e1t ho\u1eb7c Pinot Grigio nh\u1eb9 nh\u00e0ng, gi\u00fap b\u1ea1n v\u1eabn c\u00f3 ch\u00fat say n\u1ed3ng m\u00e0 kh\u00f4ng s\u1ee3 b\u1ecb nh\u1ee9c \u0111\u1ea7u d\u1eef d\u1ed9i sau \u0111\u00f3.<\/p>\n
(Theo Mentalfloss)<\/p>\n
The post L\u00fd do m\u1ed9t s\u1ed1 ng\u01b0\u1eddi kh\u00f4ng th\u1ec3 u\u1ed1ng \u0111\u01b0\u1ee3c r\u01b0\u1ee3u \u0111\u1ecf<\/a> appeared first on Saigon Nh\u1ecf<\/a>.<\/p>\n \u00a0<\/p>","protected":false},"excerpt":{"rendered":" Khi m\u1ed9t bu\u1ed5i t\u1ed1i th\u01b0 gi\u00e3n v\u1edbi m\u1ed9t ly r\u01b0\u1ee3u vang \u0111\u1ecf bi\u1ebfn th\u00e0nh c\u01a1n \u0111au \u0111\u1ea7u d\u1eef d\u1ed9i, \u0111i\u1ec1u \u0111\u00f3 t\u1ea5t nhi\u00ean s\u1ebd g\u00e2y kh\u00f3 ch\u1ecbu. \u0110\u1ed1i v\u1edbi h\u00e0ng tri\u1ec7u ng\u01b0\u1eddi, \u0111\u00e2y l\u00e0 m\u1ed9t v\u1ea5n \u0111\u1ec1 r\u1ea5t th\u1ef1c t\u1ebf v\u00e0 c\u00e1c nh\u00e0 khoa h\u1ecdc cu\u1ed1i c\u00f9ng c\u0169ng b\u1eaft \u0111\u1ea7u v\u00e0o cu\u1ed9c. H\u00f3a ra, th\u1ee7 …<\/p>","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[43],"tags":[],"class_list":["post-61734","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"_links":{"self":[{"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/posts\/61734","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/comments?post=61734"}],"version-history":[{"count":0,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/posts\/61734\/revisions"}],"wp:attachment":[{"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/media?parent=61734"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/categories?post=61734"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vietvalley.com\/en\/wp-json\/wp\/v2\/tags?post=61734"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}