{"id":49346,"date":"2024-04-04T15:12:22","date_gmt":"2024-04-04T22:12:22","guid":{"rendered":"https:\/\/vietvalley.com\/hang-duoc-tu-nguyen-ngung-ban-thuoc-dieu-tri-als-vo-tac-dung\/"},"modified":"2024-04-04T15:12:22","modified_gmt":"2024-04-04T22:12:22","slug":"hang-duoc-tu-nguyen-ngung-ban-thuoc-dieu-tri-als-vo-tac-dung","status":"publish","type":"post","link":"https:\/\/vietvalley.com\/hang-duoc-tu-nguyen-ngung-ban-thuoc-dieu-tri-als-vo-tac-dung\/","title":{"rendered":"H\u00e3ng d\u01b0\u1ee3c t\u1ef1 nguy\u1ec7n ng\u01b0ng b\u00e1n thu\u1ed1c \u0111i\u1ec1u tr\u1ecb ALS v\u00f4 t\u00e1c d\u1ee5ng"},"content":{"rendered":"

Do th\u1ea5t b\u1ea1i trong m\u1ed9t nghi\u00ean c\u1ee9u, Amylyx Pharmaceuticals tuy\u00ean b\u1ed1 r\u00fat kh\u1ecfi th\u1ecb tr\u01b0\u1eddng lo\u1ea1i thu\u1ed1c \u0111i\u1ec1u tr\u1ecb b\u1ec7nh Lou Gehrig. Theo b\u1ea3n tin AP \u0111\u0103ng h\u00f4m Th\u1ee9 N\u0103m.<\/p>\n

C\u00f4ng ty s\u1ea3n xu\u1ea5t thu\u1ed1c Amylyx Pharmaceuticals th\u1eeba nh\u1eadn lo\u1ea1i thu\u1ed1c n\u00e0y kh\u00f4ng gi\u00fap \u00edch g\u00ec cho b\u1ec7nh nh\u00e2n m\u1eafc h\u1ed9i ch\u1ee9ng ALS \u2013 c\u0103n b\u1ec7nh th\u1ea7n kinh c\u00f3 th\u1ec3 g\u00e2y ch\u1ebft ng\u01b0\u1eddi. H\u1ecd tuy\u00ean b\u1ed1 s\u1ebd t\u1ef1 nguy\u1ec7n ng\u1eebng b\u00e1n v\u00e0 ti\u1ebfp th\u1ecb thu\u1ed1c \u1edf M\u1ef9 v\u00e0 Canada, n\u01a1i nh\u1eefng b\u1ec7nh nh\u00e2n m\u1edbi kh\u00f4ng th\u1ec3 nh\u1eadn \u0111\u01b0\u1ee3c thu\u1ed1c n\u1eefa.<\/p>\n

H\u1ed9i ch\u1ee9ng ALS (vi\u1ebft t\u1eaft c\u1ee7a Amyotrophic Lateral Sclerosis), \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 b\u1ec7nh x\u01a1 c\u1ee9ng teo c\u01a1 m\u1ed9t b\u00ean, l\u00e0 b\u1ec7nh l\u00fd li\u00ean quan \u0111\u1ebfn h\u1ec7 th\u1ea7n kinh, x\u1ea3y ra khi m\u1ed9t s\u1ed1 t\u1ebf b\u00e0o n\u01a1ron \u1edf n\u00e3o v\u00e0 t\u1ee7y s\u1ed1ng d\u1ea7n ch\u1ebft \u0111i. Ng\u01b0\u1eddi b\u1ec7nh ban \u0111\u1ea7u g\u1eb7p nh\u1eefng v\u1ea5n \u0111\u1ec1 li\u00ean quan \u0111\u1ebfn c\u01a1 b\u1eafp, r\u1ed3i d\u1ea7n tr\u1edf th\u00e0nh t\u00e0n t\u1eadt, \u0111\u1ebfn cu\u1ed1i c\u00f9ng, c\u01a1 h\u00f4 h\u1ea5p ng\u1eebng ho\u1ea1t \u0111\u1ed9ng, d\u1eabn \u0111\u1ebfn t\u1eed vong.<\/p>\n

Nh\u1eefng ng\u01b0\u1eddi \u0111\u1ed3ng s\u00e1ng l\u1eadp c\u00f4ng ty th\u1eeba nh\u1eadn \u0111\u00e2y l\u00e0 th\u1eddi \u0111i\u1ec3m kh\u00f3 kh\u0103n \u0111\u1ed1i v\u1edbi c\u00e1c b\u1ec7nh nh\u00e2n ALS. Nh\u1eefng b\u1ec7nh nh\u00e2n \u0111ang d\u00f9ng li\u1ec7u ph\u00e1p n\u00e0y mu\u1ed1n ti\u1ebfp t\u1ee5c c\u00f3 th\u1ec3 ghi danh v\u00e0o m\u1ed9t ch\u01b0\u01a1ng tr\u00ecnh \u0111\u1ec3 \u0111\u01b0\u1ee3c nh\u1eadn thu\u1ed1c mi\u1ec5n ph\u00ed.<\/p>\n

C\u1ee5c Qu\u1ea3n L\u00fd Th\u1ef1c Ph\u1ea9m V\u00e0 D\u01b0\u1ee3c Ph\u1ea9m (FDA) ph\u00ea duy\u1ec7t lo\u1ea1i thu\u1ed1c g\u00e2y nhi\u1ec1u tranh c\u00e3i, Relyvrio, v\u00e0o Th\u00e1ng Ch\u00edn n\u0103m 2022, sau chi\u1ebfn d\u1ecbch v\u1eadn \u0111\u1ed9ng k\u00e9o d\u00e0i nhi\u1ec1u n\u0103m c\u1ee7a c\u00e1c b\u1ec7nh nh\u00e2n m\u1eafc h\u1ed9i ch\u1ee9ng ALS.<\/p>\n

Th\u1ea5t b\u1ea1i c\u1ee7a lo\u1ea1i thu\u1ed1c n\u00e0y l\u00e0 m\u1ed9t s\u1ef1 th\u1ea5t v\u1ecdng cay \u0111\u1eafng \u0111\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n v\u00e0 nh\u1eefng ng\u01b0\u1eddi \u1ee7ng h\u1ed9, nh\u1eefng ng\u01b0\u1eddi \u0111\u00e3 th\u00fac \u00e9p FDA v\u00e0 c\u00e1c c\u01a1 quan li\u00ean bang kh\u00e1c t\u00e0i tr\u1ee3 v\u00e0 ph\u00ea duy\u1ec7t nhi\u1ec1u li\u1ec7u ph\u00e1p th\u1eed nghi\u1ec7m h\u01a1n cho c\u0103n b\u1ec7nh nguy hi\u1ec3m g\u00e2y t\u1eed vong n\u00e0y.<\/p>\n

Nh\u01b0 v\u1eady hi\u1ec7n nay ch\u1ec9 c\u00f2n l\u1ea1i ba lo\u1ea1i thu\u1ed1c \u0111i\u1ec1u tr\u1ecb ALS, c\u00f3 s\u1eb5n cho b\u1ec7nh nh\u00e2n Hoa K\u1ef3, m\u00e0 m\u1ed9t trong s\u1ed1 \u0111\u00f3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 c\u00f3 th\u1ec3 k\u00e9o d\u00e0i th\u1eddi gian s\u1ed1ng s\u00f3t th\u00eam v\u00e0i th\u00e1ng. Theo AP.<\/p>\n

C\u0169ng trong ng\u00e0y Th\u1ee9 N\u0103m, Amylyx Pharmaceuticals c\u00f3 tr\u1ee5 s\u1edf t\u1ea1i Cambridge, Massachusetts cho bi\u1ebft h\u1ecd s\u1ebd sa th\u1ea3i 70% trong s\u1ed1 h\u01a1n 350 nh\u00e2n vi\u00ean c\u1ee7a m\u00ecnh, nh\u01b0 m\u1ed9t ph\u1ea7n c\u1ee7a n\u1ed7 l\u1ef1c t\u00e1i c\u01a1 c\u1ea5u l\u1edbn. Gi\u00e1m \u0111\u1ed1c \u0111i\u1ec1u h\u00e0nh c\u00f4ng ty n\u00f3i h\u1ecd c\u00f3 k\u1ebf ho\u1ea1ch ti\u1ebfp t\u1ee5c nghi\u00ean c\u1ee9u Relyvrio v\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c th\u1eed nghi\u1ec7m kh\u00e1c \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb m\u1ed9t s\u1ed1 b\u1ec7nh hi\u1ebfm g\u1eb7p, nh\u01b0 h\u1ed9i ch\u1ee9ng Wolfram, g\u00e2y ra b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng v\u00e0 m\u00f9 l\u00f2a \u1edf tr\u1ebb em.<\/p>\n

C\u1ed5 phi\u1ebfu c\u1ee7a c\u00f4ng ty t\u0103ng h\u01a1n 7.5% trong phi\u00ean giao d\u1ecbch s\u00e1ng Th\u1ee9 N\u0103m.<\/p>\n

Relyvrio l\u00e0 m\u1ed9t lo\u1ea1i b\u1ed9t k\u1ebft h\u1ee3p hai lo\u1ea1i thu\u1ed1c c\u0169: thu\u1ed1c k\u00ea \u0111\u01a1n \u0111i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n gan v\u00e0 th\u1ef1c ph\u1ea9m b\u1ed5 sung li\u00ean quan \u0111\u1ebfn y h\u1ecdc c\u1ed5 truy\u1ec1n Trung Qu\u1ed1c.<\/p>\n

H\u1ed9i ch\u1ee9ng ALS li\u00ean quan \u0111\u1ebfn h\u1ec7 th\u1ea7n kinh, c\u00f3 th\u1ec3 g\u00e2y ch\u1ebft ng\u01b0\u1eddi. (minh h\u1ecda: camilo Jimenez\/Unsplash)<\/p>\n

Amylyx ph\u1ea3i \u0111\u1ed1i m\u1eb7t v\u1edbi nh\u1eefng l\u1eddi ch\u1ec9 tr\u00edch v\u00ec \u0111\u1ecbnh gi\u00e1 thu\u1ed1c \u1edf m\u1ee9c $158,000 cho l\u01b0\u1ee3ng cung c\u1ea5p trong m\u1ed9t n\u0103m. M\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n \u0111\u00e3 ng\u1eebng thu\u1ed1c ch\u1ec9 sau v\u00e0i th\u00e1ng.<\/p>\n

Amylyx cho bi\u1ebft v\u00e0o th\u00e1ng tr\u01b0\u1edbc h\u1ecd \u0111ang xem x\u00e9t ng\u1eebng thu\u1ed1c sau khi th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng \u1edf 600 b\u1ec7nh nh\u00e2n m\u00e0 kh\u00f4ng cho th\u1ea5y b\u1ea5t k\u1ef3 c\u1ea3i thi\u1ec7n n\u00e0o v\u1ec1 kh\u1ea3 n\u0103ng s\u1ed1ng s\u00f3t ho\u1eb7c c\u00e1c c\u1ea3i thi\u1ec7n kh\u00e1c v\u1ec1 s\u1ee9c kh\u1ecfe, ch\u1eb3ng h\u1ea1n nh\u01b0 c\u01a1 b\u1eafp m\u1ea1nh h\u01a1n, ho\u1eb7c kh\u1ea3 n\u0103ng \u0111i l\u1ea1i.<\/p>\n

H\u00e0nh \u0111\u1ed9ng t\u1ef1 nguy\u1ec7n c\u1ee7a c\u00f4ng ty \u0111\u00e3 gi\u1ea3i quy\u1ebft \u0111\u01b0\u1ee3c nh\u1eefng g\u00ec c\u00f3 th\u1ec3 l\u00e0 m\u1ed9t v\u1ea5n \u0111\u1ec1 nan gi\u1ea3i l\u1edbn \u0111\u1ed1i v\u1edbi FDA. Vi\u1ec7c ph\u00ea duy\u1ec7t n\u0103m 2022 ch\u1ee7 y\u1ebfu d\u1ef1a tr\u00ean k\u1ebft qu\u1ea3 t\u1eeb m\u1ed9t nghi\u00ean c\u1ee9u nh\u1ecf \u1edf giai \u0111o\u1ea1n gi\u1eefa \u0111\u00e3 b\u1ecb m\u1ed9t s\u1ed1 nh\u00e0 khoa h\u1ecdc n\u1ed9i b\u1ed9 c\u1ee7a c\u01a1 quan ch\u1ec9 tr\u00edch.<\/p>\n

Th\u00f4ng th\u01b0\u1eddng, c\u01a1 quan n\u00e0y y\u00eau c\u1ea7u hai nghi\u00ean c\u1ee9u l\u1edbn \u1edf giai \u0111o\u1ea1n cu\u1ed1i cho th\u1ea5y l\u1ee3i \u00edch r\u00f5 r\u00e0ng tr\u01b0\u1edbc khi c\u1ea5p ph\u00e9p. Nh\u01b0ng v\u00e0o th\u1eddi \u0111i\u1ec3m \u0111\u00f3, c\u00e1c quan ch\u1ee9c FDA gi\u1ea3i th\u00edch r\u1eb1ng \u201ct\u00ednh linh ho\u1ea1t c\u1ee7a quy \u0111\u1ecbnh\u201d l\u00e0 ph\u00f9 h\u1ee3p khi xem x\u00e9t Relyvrio, \u201cdo t\u00ednh ch\u1ea5t nghi\u00eam tr\u1ecdng v\u00e0 \u0111e d\u1ecda t\u00ednh m\u1ea1ng c\u1ee7a ALS c\u0169ng nh\u01b0 nhu c\u1ea7u \u0111\u00e1ng k\u1ec3 ch\u01b0a \u0111\u01b0\u1ee3c \u0111\u00e1p \u1ee9ng.\u201d<\/p>\n

H\u1ed9i ch\u1ee9ng ALS c\u0169ng c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 b\u1ec7nh \u201cLou Gehrig\u201d- t\u00ean c\u1ee7a m\u1ed9t c\u1ea7u th\u1ee7 b\u00f3ng ch\u00e0y sau khi ng\u01b0\u1eddi n\u00e0y \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n m\u1eafc b\u1ec7nh n\u00eau tr\u00ean. Cho t\u1edbi nay, nguy\u00ean nh\u00e2n g\u00e2y ra b\u1ec7nh x\u01a1 c\u1ee9ng teo c\u01a1 m\u1ed9t b\u00ean v\u1eabn ch\u01b0a \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u \u0111\u1ea7y \u0111\u1ee7. M\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p \u0111\u01b0\u1ee3c cho l\u00e0 do di truy\u1ec1n.<\/p>\n

B\u1ec7nh th\u01b0\u1eddng b\u1eaft \u0111\u1ea7u v\u1edbi c\u01a1n co gi\u1eadt c\u01a1, y\u1ebfu \u1edf m\u1ed9t b\u00ean chi ho\u1eb7c n\u00f3i ch\u1eadm. B\u1ec7nh x\u01a1 c\u1ee9ng teo c\u01a1 b\u00ean tr\u00e1i \u1ea3nh h\u01b0\u1edfng ch\u1ee7 y\u1ebfu \u0111\u1ebfn c\u00e1c nh\u00f3m c\u01a1 b\u00ean tr\u00e1i c\u1ee7a c\u01a1 th\u1ec3. Cu\u1ed1i c\u00f9ng, b\u1ec7nh \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn to\u00e0n b\u1ed9 qu\u00e1 tr\u00ecnh ki\u1ec3m so\u00e1t c\u00e1c c\u01a1 c\u1ea7n thi\u1ebft \u0111\u1ec3 di chuy\u1ec3n, n\u00f3i, \u0103n v\u00e0 th\u1edf. Hi\u1ec7n nay ch\u01b0a c\u00f3 c\u00e1ch \u0111i\u1ec1u tr\u1ecb cho c\u0103n b\u1ec7nh n\u00e0y.<\/p>\n

The post H\u00e3ng d\u01b0\u1ee3c t\u1ef1 nguy\u1ec7n ng\u01b0ng b\u00e1n thu\u1ed1c \u0111i\u1ec1u tr\u1ecb ALS v\u00f4 t\u00e1c d\u1ee5ng<\/a> appeared first on Saigon Nh\u1ecf<\/a>.<\/p>\n

\u00a0<\/p>","protected":false},"excerpt":{"rendered":"

Do th\u1ea5t b\u1ea1i trong m\u1ed9t nghi\u00ean c\u1ee9u, Amylyx Pharmaceuticals tuy\u00ean b\u1ed1 r\u00fat kh\u1ecfi th\u1ecb tr\u01b0\u1eddng lo\u1ea1i thu\u1ed1c \u0111i\u1ec1u tr\u1ecb b\u1ec7nh Lou Gehrig. Theo b\u1ea3n tin AP \u0111\u0103ng h\u00f4m Th\u1ee9 N\u0103m. C\u00f4ng ty s\u1ea3n xu\u1ea5t thu\u1ed1c Amylyx Pharmaceuticals th\u1eeba nh\u1eadn lo\u1ea1i thu\u1ed1c n\u00e0y kh\u00f4ng gi\u00fap \u00edch g\u00ec cho b\u1ec7nh nh\u00e2n m\u1eafc h\u1ed9i ch\u1ee9ng ALS \u2013 c\u0103n …<\/p>\n","protected":false},"author":0,"featured_media":49347,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[82,43],"tags":[],"class_list":["post-49346","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-society","category-health"],"yoast_head":"\nH\u00e3ng d\u01b0\u1ee3c t\u1ef1 nguy\u1ec7n ng\u01b0ng b\u00e1n thu\u1ed1c \u0111i\u1ec1u tr\u1ecb ALS v\u00f4 t\u00e1c d\u1ee5ng - VietValley<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/vietvalley.com\/hang-duoc-tu-nguyen-ngung-ban-thuoc-dieu-tri-als-vo-tac-dung\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"H\u00e3ng d\u01b0\u1ee3c t\u1ef1 nguy\u1ec7n ng\u01b0ng b\u00e1n thu\u1ed1c \u0111i\u1ec1u tr\u1ecb ALS v\u00f4 t\u00e1c d\u1ee5ng\" \/>\n<meta property=\"og:description\" content=\"Do th\u1ea5t b\u1ea1i trong m\u1ed9t nghi\u00ean c\u1ee9u, Amylyx Pharmaceuticals tuy\u00ean b\u1ed1 r\u00fat kh\u1ecfi th\u1ecb tr\u01b0\u1eddng lo\u1ea1i thu\u1ed1c \u0111i\u1ec1u tr\u1ecb b\u1ec7nh Lou Gehrig. 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